PROTHENA CORP PUBLIC LTD CO (PRTA)
NASDAQ · Pharmaceuticals & Biotech · Pharmaceutical Preparations
- Price
- $8.99
- Day
- +5.64%
- Market cap
- $461.52M
Close 2026-09-22.
The company
Overview Prothena Corporation plc (“Prothena” or the “Company”) is a late-stage clinical biotechnology company with expertise in protein dysregulation with the potential to change the course of devastating neurodegenerative and rare peripheral amyloid diseases. Fueled by its deep scientific expertise built over decades of research, the Company is advancing a pipeline of therapeutic candidates for a number of indications and novel targets for which its ability to integrate scientific insights around neurological dysfunction and the biology of misfolded proteins can be leveraged. The Company’s pipeline includes both wholly-owned and partnered programs being developed for the potential treatment of diseases including Parkinson’s disease, ATTR amyloidosis with cardiomyopathy, Alzheimer’s disease, Amyotrophic lateral sclerosis (ALS) and a number of other neurodegenerative diseases. Prothena is developing and applying its proprietary CYTOPE® technology to target a broad spectrum of intracellular disease pathways in the brain and periphery. The Company was formed on September 26, 2012, under the laws of Ireland and re-registered as an Irish public limited company on October 25, 2012. The Company's ordinary shares began trading on The Nasdaq Global Market under the symbol “PRTA” on December 21, 2012, and currently trade on The Nasdaq Global Select Market.
From Item 1: Overview.
By product & service
- Collaboration — 100%
- License — 0%
Institutional holders
Largest positions reported on Form 13F for the quarter ended 2026-06-30, by value.
- Rubric Capital Management LP — $48.95M
- FMR LLC — $37.82M
- FMR LLC — $32.66M
- STATE STREET CORP — $23.43M
- BlackRock, Inc. — $19.61M
- BlackRock, Inc. — $16.46M
- VANGUARD PORTFOLIO MANAGEMENT LLC — $16.17M
- D. E. Shaw & Co., Inc. — $15.78M
Insider trades
Open-market buys and sales filed on Form 4, newest first. Grants, option exercises and tax withholding are left out.
- SCULLY WILLIAM P (TenPercentOwner) bought 100,000 shares at $8.43 on 2026-09-18
- SCULLY WILLIAM P (TenPercentOwner) bought 27,000 shares at $9.47 on 2026-09-02
- SCULLY WILLIAM P (TenPercentOwner) bought 50,000 shares at $8.79 on 2026-08-20
- SCULLY WILLIAM P (TenPercentOwner) bought 34,000 shares at $8.62 on 2026-08-07
- SCULLY WILLIAM P (TenPercentOwner) bought 3,500 shares at $8.62 on 2026-08-07
- Kingston Anne Evans (Chief Strategy Officer) sold 7,662 shares at $8.47 on 2026-07-29
Recent filings
- 4 — 2026-09-21
- 4 — 2026-09-03
- 4 — 2026-08-21
- SCHEDULE 13G/A — 2026-08-19
- 3 — 2026-08-18
- 4 — 2026-08-18
- SCHEDULE 13G/A — 2026-08-14
- 4 — 2026-08-11
- 3 — 2026-08-11
- 4 — 2026-08-10