OPKO HEALTH, INC. (OPK)
NASDAQ · Pharmaceuticals & Biotech · Pharmaceutical Preparations
- Price
- $1.64
- Day
- -3.53%
- Market cap
- $1.22B
Close 2026-09-24.
The company
OVERVIEW We are a diversified healthcare company that seeks to establish industry-leading positions in large and rapidly growing medical markets. Our pharmaceutical business features NGENLA ® (somatrogon-ghla), also referred to as Somatrogon (hGH-CTP), a once-weekly human growth hormone injection. We have partnered with Pfizer Inc. (“Pfizer”) for further development and commercialization of Somatrogon (hGH-CTP). Regulatory approvals for Somatrogon (hGH-CTP) for the treatment of children and adolescents as young as three years of age with growth disturbance due to insufficient secretion of growth hormone, have been secured in more than 50 markets worldwide, including in the United States, European Union Member States, Japan, Canada, and Australia under the brand name NGENLA ® . Through our pharmaceutical business, we manufacture and sell Rayaldee , a U.S. Food and Drug Administration (“FDA”) approved treatment for secondary hyperparathyroidism (“SHPT”) in adults with stage 3 or 4 chronic kidney disease (“CKD”) and vitamin D insufficiency. Rayaldee has secured marketing authorizations in 11 European countries, and we are advancing its development in mainland China through our strategic partners. Our subsidiary, ModeX Therapeutics, Inc. (“ModeX”), is a biotechnology company focused on developing innovative multi-specific immune therapies for cancer and infectious disease candidates.
From Item 1: OVERVIEW.
By product & service
- Service — 61%
- Product — 26%
- Transfer Of Intellectual Property and Other — 13%
Institutional holders
Largest positions reported on Form 13F for the quarter ended 2026-06-30, by value.
- Rubric Capital Management LP — $71.69M
- BlackRock, Inc. — $28.71M
- VANGUARD CAPITAL MANAGEMENT LLC — $22.45M
- VANGUARD PORTFOLIO MANAGEMENT LLC — $22.4M
- BlackRock, Inc. — $19.31M
- STATE STREET CORP — $15.46M
- GEODE CAPITAL MANAGEMENT, LLC — $15.05M
- GOLDMAN SACHS GROUP INC — $9.44M
Insider trades
Open-market buys and sales filed on Form 4, newest first. Grants, option exercises and tax withholding are left out.
- PAGANELLI JOHN A (Director) bought 10,000 shares at $1.14 on 2026-03-20
- Frost Gamma Investments Trust (TenPercentOwner) bought 89,375 shares at $1.33 on 2025-11-21
- Frost Gamma Investments Trust (TenPercentOwner) bought 191,490 shares at $1.33 on 2025-11-21
- Frost Gamma Investments Trust (TenPercentOwner) bought 3,894 shares at $1.32 on 2025-11-21
- Frost Gamma Investments Trust (TenPercentOwner) bought 102,371 shares at $1.30 on 2025-11-21
- Frost Gamma Investments Trust (TenPercentOwner) bought 192,870 shares at $1.34 on 2025-11-21
Recent filings
- 10-Q/A — 2026-08-28
- 10-Q/A — 2026-08-28
- 8-K — 2026-08-14
- SCHEDULE 13D — 2026-08-07
- 4 — 2026-07-28
- 4 — 2026-07-28
- 10-Q — 2026-07-27
- 8-K — 2026-07-27
- SCHEDULE 13D/A — 2026-07-01
- 4 — 2026-06-22