Aktis Oncology, Inc. (AKTS)
NASDAQ · Pharmaceuticals & Biotech · Pharmaceutical Preparations
- Price
- $22.11
- Day
- +3.17%
- Market cap
- $1.22B
Close 2026-09-22.
The company
Our pipeline We are leveraging our proprietary miniprotein radioconjugate platform to discover and develop a deep pipeline of targeted radiopharmaceutical programs to address unmet needs in prevalent solid tumors. Our most advanced program, [ 225 Ac]Ac-AKY-1189, is targeting Nectin-4 expressing solid tumors, including locally advanced or metastatic UC, breast cancer, NSCLC, colorectal cancer and cervical cancer. Our second most advanced program, [ 225 Ac]Ac-AKY-2519, is targeting B7-H3 expressing solid tumors, such as prostate, lung and breast cancers. Beyond [ 225 Ac]Ac-AKY-1189 and [ 225 Ac]Ac-AKY-2519, we have a robust discovery pipeline of several unpartnered miniprotein radioconjugate programs in the discovery phase that focus on clinically-validated targets. Our learnings from the optimization of [ 225 Ac]Ac-AKY-1189 are being applied to benefit the development of [ 225 Ac]Ac-AKY-2519 and these subsequent programs. We retain exclusive, worldwide development and commercialization rights to all our current product candidates and discovery programs. We also have a discovery collaboration with Eli Lilly and Company, or Eli Lilly, to generate novel anticancer radiopharmaceuticals against targets beyond the scope of our unpartnered pipeline programs.
From Item 1: Our pipeline.
Institutional holders
Largest positions reported on Form 13F for the quarter ended 2026-06-30, by value.
- MPM BIOIMPACT LLC — $155.86M
- EcoR1 Capital, LLC — $155.49M
- Blue Owl Capital Holdings LP — $98.95M
- WELLINGTON MANAGEMENT GROUP LLP — $62.96M
- RTW INVESTMENTS, LP — $51.31M
- RA CAPITAL MANAGEMENT, L.P. — $42.36M
- Jupiter Topco LLC — $42.36M
- BAKER BROS. ADVISORS LP — $32.11M
Insider trades
Open-market buys and sales filed on Form 4, newest first. Grants, option exercises and tax withholding are left out.
- Herrmann Ken (Director) sold 3,506 shares at $24.56 on 2026-07-20
- Herrmann Ken (Director) sold 1,350 shares at $24.56 on 2026-07-20
- Herrmann Ken (Director) sold 3,065 shares at $25.21 on 2026-07-17
- Ron-Bigger Shulamit (Chief Operating Officer) sold 15,800 shares at $27.13 on 2026-07-08
- Ron-Bigger Shulamit (Chief Operating Officer) sold 30,000 shares at $27.94 on 2026-07-08
- Ron-Bigger Shulamit (Chief Operating Officer) sold 4,200 shares at $28.75 on 2026-07-08
Recent filings
- 10-Q — 2026-08-13
- 8-K — 2026-08-13
- 4 — 2026-07-21
- 4 — 2026-07-20
- 144 — 2026-07-20
- 144 — 2026-07-17
- 4 — 2026-07-10
- 4 — 2026-07-10
- 144 — 2026-07-08
- 144 — 2026-07-08